产品介绍
Product Description
Biochem/physiol Actions
ZLN005 is a transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α). ZLN005 increased PGC-1 and downstream gene transcription in skeletal muscle, while reducing hepatic PGC-1α and gluconeogenesis genes. ZLN005 increased fat oxidation and improved the glucose tolerance, pyruvate tolerance, insulin sensitivity, hyperglycemia and dyslipidemia of diabetic db/db mice.
ZLN005 is a transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥95% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 10 mg/mL, clear |
| storage temp. | −20°C |
| SMILES string | [nH]1c2c(nc1c3ccc(cc3)C(C)(C)C)cccc2 |
| InChI | 1S/C17H18N2/c1-17(2,3)13-10-8-12(9-11-13)16-18-14-6-4-5-7-15(14)19-16/h4-11H,1-3H3,(H,18,19) |
| InChI key | LQUNNCQSFFKSSK-UHFFFAOYSA-N |
