General description
Anti-KCNJ5 Antibody detects endogenous levels of total KCNJ5 protein.
KCNJ5 (potassium voltage-gated channel subfamily J member 5) is an inwardly rectifying potassium channel, which is also termed as GIRK4 (G protein-coupled inward rectifier K+ channel 4). It is expressed in the cerebral cortex. This gene is mapped to human chromosome 11q24.
Immunogen
The antiserum was produced against synthesized peptide derived from human KCNJ5.
Immunogen Range: 370-419
Biochem/physiol Actions
KCNJ5 (potassium voltage-gated channel subfamily J member 5) is associated with aldosteronism, a major cause of secondary hypertension. Mutated KCNJ5 gene affects the polarization of plasma membrane and permit sodium and calcium inflow into the cells.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 47 kDa |
| species reactivity | human |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:5000,immunofluorescence: 1:100-1:500,western blot: 1:500-1:1000 |
| NCBI accession no. | P48544 |
| UniProt accession no. | P48544 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... KCNJ5(3762) |
