General description
Chemical structure: β-lactam
Application
Cefotaxime sodium salt has been used as an test antibiotic in antibiotic susceptibility testing (AST) methods. It has also been used as an antibiotic to remove bacteria from O. tauri cultures.
Biochem/physiol Actions
Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria. It also has an ability to inhibit the cell division of lower plant organelles/plastids such as the photosynthetic organelles of glaucophytes and chloroplasts of bryophytes.
Mode of Action: Inhibits bacterial cell wall synthesis.
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Other Notes
Broad spectrum third generation cephalosporin antibiotic.
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.
| product line | BioReagent |
| Quality Level | 200 |
| form | powder or crystals |
| technique(s) | cell culture | plant: suitable |
| color | off-white to pale yellow |
| solubility | H2O: 10% ( ) |
| antibiotic activity spectrum | Gram-negative bacteria,Gram-positive bacteria |
| application(s) | agriculture |
| mode of action | cell wall synthesis | interferes |
| storage temp. | 2-8°C |
| SMILES string | [Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O |
| InChI | 1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1 |
| InChI key | AZZMGZXNTDTSME-JUZDKLSSSA-M |
