Biochem/physiol Actions
Nicotinic acid riboside (NAR, NR), an orally bioavailable Vitamin B3 derivative and authentic nicotinamide adenine dinucleotide (NAD+) intermediate, primarily functions to elevate intracellular NAD+ levels. Following cellular uptake via transporters, NAR is converted to NAD+ through the Preiss-Handler pathway, initiated by NR kinases. This NAD+ increase is crucial as NAD+ is vital for essential cellular processes like energy metabolism, DNA repair, and sirtuin activation, which are often impaired with age. Consequently, NAR holds significant therapeutic potential by restoring NAD+ to support cellular health and mitigate age-related and metabolic dysfunction, thereby enhancing cellular resilience and function.
Disclaimer
Hygroscopic Store with desiccant
| Quality Level | 100 |
| assay | ≥95% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| solubility | H2O: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
