产品介绍
Product Description
Biochem/physiol Actions
DRF053 is a more potent version of roscovitine.
DRF053 is a more potent version of roscovitine. It is 2 fold more potent against CDK5 (80 nM) and over 150 times more potent against CDK1 (14 nM).
Features and Benefits
This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| color | yellow |
| solubility | DMSO: ≥30 mg/mL |
| storage temp. | 2-8°C |
| SMILES string | O.Cl.CC[C@H](CO)Nc1nc(Nc2cccc(c2)-c3ccccn3)c4ncn(C(C)C)c4n1 |
| InChI | 1S/C23H27N7O.ClH.H2O/c1-4-17(13-31)27-23-28-21(20-22(29-23)30(14-25-20)15(2)3)26-18-9-7-8-16(12-18)19-10-5-6-11-24-19;;/h5-12,14-15,17,31H,4,13H2,1-3H3,(H2,26,27,28,29);1H;1H2/t17-;;/m1../s1 |
| InChI key | ZOSNTFVWVJFXQO-ZEECNFPPSA-N |
