General description
MBTD1 (Mbt domain containing 1) is a member of Polycomb group (PcG) of proteins consisting of four MBT repeats, which form an asymmetric rhomboid architecture and a FCS-type zinc finger at the N-terminus end with putative regulatory function.
Application
ANTI-MBTD1 (C-TERM) antibody produced in rabbit is suitable for immunohistochemistry at a dilution of 1:50-1:100 and western blot at a dilution of 1:250-1:500
Biochem/physiol Actions
MBTD1 (Mbt domain containing 1) is involved in the developmental regulation. MBT group of proteins help to suppress the transcriptional expression of developmental control genes. It has been studied that MBT domain of the protein binds to mono-methylated and dimethylated ′Lys-20′ on histone H4 during the determination of histone binding ability of MBTD1.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 70547 Da |
| species reactivity | mouse, human |
| technique(s) | immunohistochemistry: 1:50-1:100,western blot: 1:1000 |
| NCBI accession no. | NP_060113.2 |
| UniProt accession no. | Q05BQ5 |
| shipped in | wet ice |
| storage temp. | −20°C |
