产品介绍
Product Description
Clone REA1040 recognizes the human CD226 (DNAM-1) antigen, a 65 kDa transmembrane glycoprotein expressed on T cells, NK cells, platelets, monocytes, and a subset of B cells. It is also expressed by a subset of CD3+ thymocytes. The surface association of CD226 (DNAM-1) with LFA-1 on NK cells and T cells permits the transduction of cytolytic signals upon binding of CD226 (DNAM-1) to its ligands CD155 (PVR) and CD112 (Nectin-2).
Additional information: Clone REA1040 displays negligible binding to Fc receptors.
DNAM-1, PTA-1, TLiSA1
Technical specifications
