Clone REA318 recognizes the mouse T cell receptor beta chain (TCRβ). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRα/β T cells, though a minority of T cells express an alternate receptor, formed by variable gamma and delta chains, referred as TCRγ/δ T cells. TCRβ is expressed on TCRα/β T cells and thymocytes, NK1.1+ thymocytes and NK-T cells.
Additional information: Clone REA318 displays negligible binding to Fc receptors.
TCRB, TCRbeta, Tib
Technical specifications
