产品介绍
Product Description
Clone REA1211 recognizes the mouse CD4 antigen, a cell surface glycoprotein, which is a member of the immunoglobulin superfamily. It is also known as L3T4 or Leu-3. In mice, CD4 is expressed on T helper cells, regulatory T cells, and at lower levels on subpopulations of NKT cells and dendritic cells. It is furthermore detected on most thymocytes (CD4+CD8+ and CD4+CD8– thymocytes). CD4 interacts with MHC class II molecules on the surface of antigen presenting cells. It increases the avidity of the interaction between T cells and antigen-presenting or target cells.
Additional information: Clone REA1211 displays negligible binding to Fc receptors.
L3T4, T4, Leu-3, Ly-4
Technical specifications
