规格
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Accession Number:
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NP_940980.2 |
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Assay Entry:
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Biochemical terbium phospho-specific activity, Biochemical binding/kinetic |
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Form:
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Frozen |
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Kinase Group:
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Ser⁄Thr Kinases: TKL Group |
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Protein Form:
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Catalytic |
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Research Category:
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Signal Transduction, Neurobiology |
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Shipping Condition:
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Dry Ice |
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Species:
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Human |
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System Compatibility:
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LanthaScreen®, Adapta™ |
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Tag Position:
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N-Terminal |
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Target Entry:
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LRRK2 I2020T |
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Target Gene:
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LRRK2 I2020T |
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Molecular Weight:
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205 kDa |
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Protein Subtype:
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Serine⁄Threonine Kinases |
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Gene Alias:
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LRRK2 I2020T |
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Validated Application:
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Kinase Assay |
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Protein Family:
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Kinases & Inhibitors |
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Expression System:
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Baculovirus |
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KinaseFamily:
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LRRK Kinase Family |
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Protein Tag:
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GST Tag |
储存
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Kinase proteins are shipped on dry ice and should be stored at -80°C. |
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease, including the I2020T mutation in the kinase catalytic domain.
Related Links:
• LRRK2 tools for advancing Parkinson's disease research
• Kinase protein portfolio
• LanthaScreen® Eu Kinase Binding Assay
• LanthaScreen® Activity Assay
