CD317 (PDCA-1)-Biotin, mouse, 100 tests，130-123-459，美天旎

Clone JF05-1C2.4.1 specifically recognizes the mouse CD317 antigen, also known as plasmacytoid dendritic cell antigen-1 (PDCA-1). CD317 is specifically expressed on mouse PDCs, a subset of CD11c⁺ dendritic cells detected at low frequency in all lymphoid tissues, peripheral blood, and some non-lymphoid tissues.

In mouse spleen, bone marrow, and lymph nodes, CD317 is exclusively expressed on cells which are CD11c^low, Ly-6C^high, CD45R (B220)⁺, MHC class II^low, CD8a^low/–, CD80^low/–, CD86^–, CD40^–, CD11b^–, CD90^–, CD49b (DX5)^–, CD3^–, CD19^–, i.e. on cells with the phenotype of mouse PDCs. Multi-color fluorescent staining of spleen cells clearly revealed that all CD11c^low Ly-6C^high CD45R (B220)⁺ PDCs are PDCA-1⁺ and that PDCA-1 expression is restricted to PDCs.

BST2, Bst-2, C87040, mPDCA-1, DAMP-1, GREG

Technical specifications