产品介绍
Product Description
Clone REA758 recognizes the human FcεRIα, the α subunit of the human high-affinity Fc receptor for IgE. The receptor is composed of one α-, one β-, and two disulphide-linked γ-chains, of which the α subunit binds IgE1. FcεRIα is expressed on mast and basophil cells, is upregulated in the presence of IgE, and is found on a subset of blood dendritic cells. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions.
Additional information: Clone REA758 displays negligible binding to Fc receptors.
FCER1A, Fce1a, FcERI
Technical specifications
