产品介绍
Product Description
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规格 |
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| Accession Number: | NP_002637.2 |
| Assay Entry: | Biochemical ADP accumulation |
| Form: | Frozen |
| Kinase Group: | Lipid Kinases |
| Mass: | 20 µg |
| Protein Form: | Recombinant, Catalytic |
| Reactivity: | Human |
| Research Category: | Signal Transduction |
| Shipping Condition: | Dry Ice |
| Species: | Human |
| System Compatibility: | Adapta™ |
| Tag Position: | N-Terminal |
| Target Entry: | PIK3C2B |
| Target Gene: | phosphoinositide-3-kinase, class 2, beta polypeptide |
| Molecular Weight: | 167 kDa |
| Purity: | 35 % |
| Protein Subtype: | Lipid Kinases |
| Gene Alias: | PIK3C2B (PI3K-C2 beta) |
| Validated Application: | Kinase Assay |
| Protein Family: | Kinases & Inhibitors |
| Expression System: | Baculovirus |
| KinaseFamily: | PI3 Kinase Family |
| Protein Length: | aa 155-1383 |
| Protein Tag: | GST Tag |
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储存 |
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Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
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描述 |
The class II PI3 kinases, including PIK3C2B, phosphorylate the 3 position of PI or PI4P. Though not as well studied as the class I PI3 kinases, the class II enyzmes have been linked to diverse, recpetor-mediated cellular processes including insulin signalling, neuronal survival, and growth factor signalling.
