General description
ID4 is an inhibitor of differentiation protein, which, along with ID1, ID2 and ID3, plays a key role in the regulation of lineage commitment, cell fate decisions and in the timing of differentiation during neurogenesis, lymphopoiesis and neovascularisation (angiogenesis). ID proteins, induced by the bone morphogenic protein-SMAD pathway, have also been shown to cooperate with LIF to ensure that embryonic stem cells opt for self-renewal.
~17 kDa observed
Immunogen
KLH-conjugated linear peptide corresponding to human ID4.
Application
Use Anti-ID4 Antibody, clone DML07 (Mouse Monoclonal Antibody) validated in WB to detect ID4 also known as DNA-binding protein inhibitor ID-4, Class B basic helix-loop-helix protein 27, bHLHb27.
Western Blot Analysis: 1 µg/mL from a representative lot detected ID4 on 10 µg of mouse lymph node tissue lysate.
Physical form
Format: Purified
Analysis Note
Evaluated by Western Blot in human lung tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected ID4 on 10 µg of human lung tissue lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | DML07, monoclonal |
| species reactivity | mouse, human |
| technique(s) | western blot: suitable |
| isotype | IgG2bκ |
| NCBI accession no. | NP_001537 |
| UniProt accession no. | P47928 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... ID4(3400) |
