General description
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein.
~31 kDa observed.
Band may migrate from the calculated 29 kDa to ~31 kDa on western blot.
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human KLK3.
Application
This Anti-Kallikrein-3 (KLK3) (C-term) Antibody is validated for use in WB for the detection of Kallikrein-3 (KLK3) (C-term).
Biochem/physiol Actions
Other species have not been tested.
The antibody reacts with the 29 kDa KLK3 antigen.
Physical form
Format: Purified
Saturated Ammonium Sulfate (SAS)
Preparation Note
Store at 2-8°C for 6 months from date of receipt. For long term storage, store at -20°
Analysis Note
Control
Western Blot : Mouse brain lysate.
Western Blot Analysis: 1:250 dilution of this antibody detected KLK3 on mouse brain lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | saturated ammonium sulfate (SAS) precipitated |
| antibody product type | primary antibodies |
| clone | polyclonal |
| species reactivity | mouse, rat, human |
| technique(s) | western blot: suitable |
| NCBI accession no. | NP_001639 |
| UniProt accession no. | P07288 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... KLK3(354) |
