Immunogen
Epitope: KPI domain
Purified recombinant KPI domain of Amyloid-beta precursor protein.
Application
Anti-Amyloid β Precursor Protein Antibody, KPI domain, clone 4.1 detects level of Amyloid β Precursor Protein & has been published & validated for use in ELISA, WB, IH.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Western blot: 2-5 μg/mL using ECL on human brain or platelets. Recognizes a protein of 100-120 kDa.
Immunohistochemistry: 2-5 μg/mL on frozen tissue sections.
ELISA: 1 μg/mL in a direct assay and 10 μg/mL in an indirect assay.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Amyloid-beta Precursor Protein, KPI (Kunitz protease inhibitor) domain. The antibody reacts with both native and recombinant protein. The antibody has been shown to partially inhibit protease inhibitory properties.
Physical form
Format: Purified
Purified immunoglobulin. Liquid in 20 mM Sodium phosphate buffer with 150 mM NaCl.
Preparation Note
Maintain at 2-8°C in undiluted aliquots for up to 6 months of date of receipt.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 4.1, monoclonal |
| species reactivity | human |
| manufacturer/tradename | Chemicon® |
| technique(s) | ELISA: suitable,immunohistochemistry: suitable,western blot: suitable |
| isotype | IgG1 |
| NCBI accession no. | NM_000484.2,NM_201413.1,NM_201414.1 |
| UniProt accession no. | P05067 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... APP(351) |
