General description
Glutathione S-transferase (GST) belongs to three families of proteins distinguished as cytosolic, mitochondrial, and microsomal GST. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: α,
Biochem/physiol Actions
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in phase II detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
Physical form
50mM Tris-HCl, pH 8, 150mM NaCl, 20% glycerol
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
| form | liquid |
| Quality Level | 100 |
| manufacturer/tradename | Upstate® |
| technique(s) | affinity chromatography: suitable |
| NCBI accession no. | NM_000852.2 |
| UniProt accession no. | P09211 |
| shipped in | dry ice |
