MILLIPLEX®人细胞因子/趋化因子/生长因子组合A 48 Plex预混合磁珠试剂盒-免疫学多重分析，1EACH，HCYTA-60K-PX48，密理博

General description

Cytokines, chemokines, and growth factors are key mediatorsof immune system functions capable of signaling through autocrine, paracrine,and endocrine mechanisms. Their pleiotropic immunomodulatory propertiesallow these biomolecules to react to diverse stimuli and regulate the immuneresponse, either promoting or inhibiting inflammation.

Application

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 48 analytes in human serum, plasma, and cell culture supernatants.

Analytes included: sCD40L, EGF, Eotaxin/CCL11, FGF-2/FGF-basic, FLT-3L, Fractalkine/CX3CL1, G-CSF, GM-CSF, GROα, IFNα2, IFNγ, IL-1α, IL-1β, IL-1RA, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12 (p40), IL-12(p70), IL-13, IL-15, IL-17A/CTLA8, IL-17E/IL-25, IL-17F, IL-18, IL-22, IL-27, IP-10/CXCL10, MCP-1/CCL2, MCP-3/CCL7, M-CSF, MDC, MIG/CXCL9, MIP-1α/CCL3, MIP-1β/CCL4, PDGF-AA, PDGF-AB/BB, RANTES/CCL5, TGFα, TNFα, TNFβ/LTA, VEGF-A

Note: RANTES cannot be plexed with other cytokines in this panel due to a required 1:100 dilution of plasma/serum samples. This premixed panel comes with a RANTES bead, so please plan your samples accordingly.

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

• Lead the Field with 48-Plex Precision: The ability to profile 48 analytes simultaneously means researchers can uncover intricate cytokine interactions and pathways that are essential for understanding complex diseases.
• Confidence in Results with Cross-Reactivity Testing: Enhanced verification means you can publish your findings with greater assurance, knowing that your data is backed by thorough testing protocols.
• Disease Profiling Power: Proven utility in profiling immune responses in cancer, sepsis, IBD, and autoimmune diseases. Detects subtle changes in cytokine levels across disease states.
• High Biological Relevance: Analytes selected for their roles in inflammation, immune regulation, angiogenesis, and cell signaling, including key biomarkers like IL-6, TNFα, IL-10, VEGF-A, and PDGF-BB.
• Peer-Reviewed Validation: Extensively cited in immunology and disease research publications. Trusted by academic and clinical researchers worldwide.

Legal Information

Luminex is a registered trademark of Luminex Corporation
xMAP is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.