Immunogen
Peptide corresponding to the C-terminus of the rat NMDAR1 C2 splice variant.
Application
This Anti-NMDAR1 Splice Variant C2 Antibody is validated for use in IH, WB for the detection of NMDAR1 Splice Variant C2.
Western blot: 1:1000 using ECL
Immunohistochemistry: 1:1,000
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Specific for the NMDAR1 C2 splice variants. Recognizes NMDAR-1a, 1b, 2a, and 2b NR1 splice variants. {Gorter et al, (1997), "The Role of Alternative Splicing of the NMDAR1 Receptor Subunit in Synaptic Plasticity" Chapter 4, pg 99, in The Ionotropic Glutamate Receptors , Monaghan, D.T. and Weinhold, R.J. (eds), Humana Press, New Jersey) By Western blot the antibody recognizes a protein with molecular weight of 120 kDa.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | rat, mouse |
| packaging | antibody small pack of 25 μg |
| manufacturer/tradename | Chemicon® |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| NCBI accession no. | NM_000832.5,NM_007327.2,NM_021569.2 |
| UniProt accession no. | Q05586 |
| shipped in | dry ice |
| target post-translational modification | unmodified |
| Gene Information | mouse ... Grin1(14810) rat ... Grin1(24408) |
