产品介绍
Product Description
General description
Inhibits matrix metalloproteinase-3 (stromelysin) (IC50 = 5 µM). The inhibitor is based on a segment from the conserved region of the NH2-terminal propeptide domain.
Inhibits the matrix metalloproteinase MMP-3 (IC50 = 5 µM).
Biochem/physiol Actions
Cell permeable: no
Primary Target
MMP-3
Product does not compete with ATP.
Reversible: no
Target IC50: 5 µM against MMP-3
Physical form
Supplied as a trifluroacetate salt.
Preparation Note
Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.
Other Notes
Ac-Arg-Cys-Gly-Val-Pro-Asp-NH₂
Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥90% (HPLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,desiccated (hygroscopic) |
| color | white |
| solubility | water: 1 mg/mL |
| shipped in | ambient |
| storage temp. | −20°C |
