产品详情

Phosphodiesterase 4B2, His•Tag®, Human, Recombinant, S. frugiperda,10U,524736-10UCN,Sigma

销售价: ¥ 4382.07 / 件
优    惠: 请询价
订货号 : 0BV5898
品牌型号 : 524736-10UCN
货期 : 询货期
最小订货量 : 1件
产品介绍 Product Description

General description

Full-length, recombinant, human phosphodiesterase 4B2 (accession no. L20971) fused at the N-terminus to a His•Tag sequence and expressed in S. frugiperda using a baculovirus expression system. Plays a significant role in the regulation of inflammatory cell activation. PDE4B2 is a predominant isoform in neutrophils and monocytes. Supplied as a partially purified, catalytically active preparation.


Physical form

In 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.


Preparation Note

Following initial thaw, aliquot and freeze (-70°C).


Other Notes

Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol.538, 39.
Smith, P.G., et al. 2005 Blood105, 308.
Baroja, M.L., et al. 1999. J. Immunol.162, 2016.
One unit is defined as the amount of enzyme that will convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Standard Handling (A)


技术参数 Specifications
recombinantexpressed in baculovirus infected Spodoptera frugiperda cells
Quality Segment100
formliquid
specific activity≥0.25 U/μL
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze,avoid repeated freeze/thaw cycles
shipped inwet ice
storage temp.−70°C
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