产品介绍
Product Description
General description
Cell permeable: No
Product does not compete with ATP.
Reversible: No
Chymostatin is a naturally occurring inhibitor of serine proteases with chymotryptic-like specificity. This tetrapeptide inhibitor is produced by various species of Streptomyces bacteria. Chymostatin is used as an inhibitor of MC chymase and is also capable of inhibiting several other proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, and lysosomal cysteine proteinases such as cathepsins B, H, andL. Itcontains chymostatin "A" as a major form.
Application
Chymostatin has been used as a:
- cysteine protease inhibitor in thesubstrate to measure the activated FX (FXa) activity
- protease inhibitor in enzyme purificationlysis buffer
- protease inhibitor for ISW2 protein complexpurification
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
技术参数
Specifications
| Quality Segment | 100 |
| description | RTECS - GC3047700 |
| form | powder,solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze |
| color | white to slightly yellow |
| solubility | 5% glacial acetic acid: 10 mg/mL,DMSO: 20 mg/mL |
| shipped in | ambient |
| storage temp. | 2-8°C |
| SMILES string | N7C(CCNC7=N)[C@H](NC(=O)N[C@@H](Cc9ccccc9)C(=O)O)C(=O)N[C@@H]([C@H](CC)C)C(=O)N[C@@H](Cc8ccccc8)C=O.N4C(CCNC4=N)[C@H](NC(=O)N[C@@H](Cc6ccccc6)C(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc5ccccc5)C=O.N1C(CCNC1=N)[C@H](NC(=O)N[C@@H](Cc3ccccc3)C(=O)O)C(=O)N[C@@ |
| InChI | 1S/2C31H41N7O6.C30H39N7O6/c1-19(2)15-24(27(40)34-22(18-39)16-20-9-5-3-6-10-20)35-28(41)26(23-13-14-33-30(32)36-23)38-31(44)37-25(29(42)43)17-21-11-7-4-8-12-21;1-3-19(2)25(27(40)34-22(18-39)16-20-10-6-4-7-11-20)37-28(41)26(23-14-15-33-30(32)35-23)38-31(44)36-24(29(42)43)17-21-12-8-5-9-13-21;1-18(2)24(26(39)33-21(17-38)15-19-9-5-3-6-10-19)36-27(40)25(22-13-14-32-29(31)34-22)37-30(43)35-23(28(41)42)16-20-11-7-4-8-12-20/h3-12,18-19,22-26H,13-17H2,1-2H3,(H,34,40)(H,35,41)(H,42,43)(H3,32,33,36)(H2,37,38,44);4-13,18-19,22-26H,3,14-17H2,1-2H3,(H,34,40)(H,37,41)(H,42,43)(H3,32,33,35)(H2,36,38,44);3-12,17-18,21-25H,13-16H2,1-2H3,(H,33,39)(H,36,40)(H,41,42)(H3,31,32,34)(H2,35,37,43)/t22-,23?,24-,25-,26-;19-,22-,23?,24-,25-,26-;21-,22?,23-,24-,25-/m000/s1 |
| InChI key | QJIJPLFVFWXMGK-KSPFWWQASA-N |
