General description
Brain link protein 1 (BRAL1) is a member a superfamily consisting of several highly homologous hyaluronan and proteoglycan binding link proteins. BRAL1 is predominantly expressed in brain tissue and spinal cord. Like other members in the link-module superfamily, BRAL1 contains an immunoglobulin-like fold and two proteoglycan tandem repeats (PTRs). Its mRNA expression pattern is similar to other lectican proteoglycans, suggesting that BRAL1 may act to stabilize the binding between the extracellular matrix molecule hyaluronan and brevican. Immunostaining of mouse brain showed BRAL1 expression at P20 in the white matter of the developing cerebellum and in myelinated fiber tracts in the adult brain, suggesting that expression starts when axonal myelination occurs.
~36 kDa observed
Immunogen
KLH-conjugated linear peptide corresponding to human BRAL1.
Application
Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected BRAL1 in human brain tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
Anti-BRAL1 detects levels of BRAL1 proteins & has been published & validated for use in WB & IHC.
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Human brain tissue lysate
Evaluated by Western Blot in human brain tissue lysate.
Western Blot Analysis: 2 µg/mL of this antibody detected BRAL1 in 15 µg of human brain tissue lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| UniProt accession no. | Q9GZV7 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... HAPLN2(60484) |
