General description
Visual arrestin is a 48 kDa protein expressed exclusively in retinal photoreceptor cells where it regulates light-dependent signal transduction through G protein-coupled receptor (rhodopsin) activation. Visual arrestin is the major pathogenetic autoantigen in human autoimmume imflammatory eye disease.
Immunogen
Porcine visual arrestin.
Application
Detect Arrestin using this Anti-Arrestin Antibody, visual validated for use in IH, IP & WB.
Research Category
Neuroscience
Research Sub Category
Sensory & PNS
Western blot: 48kDa
Immunohistochemistry
Immunopurification of arrestin
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Visual arrestin. The antibody has not been tested for reactivity to arrestin in other tissues.
Physical form
Ascites fluid. Liquid.
Preparation Note
Maintain -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| clone | monoclonal |
| species reactivity | rat, human, pig, bovine, goat, sheep |
| manufacturer/tradename | Chemicon® |
| technique(s) | immunohistochemistry: suitable,immunoprecipitation (IP): suitable,western blot: suitable |
| isotype | IgG1 |
| UniProt accession no. | P79260 |
| shipped in | dry ice |
| target post-translational modification | unmodified |
| Gene Information | human ... SAG(6295) |
