产品介绍
Product Description
Biochem/physiol Actions
AZD1283 is potent non-nucleotide P2Y12 antagonist with a Kd value of 11 nM. It had good antithrombotic activity, inhibiting ADP-induced platelet aggregation. AZD1283 has been used to study the structure of the human P2Y12 receptor.
Potent P2Y12 antagonist with antithrombotic activity
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| color | orange to brown |
| solubility | DMSO: 2 mg/mL, clear |
| web metadata keyword.default | AZD1283 100mg P2Y12 receptor study,AZD1283 500mg research chemical,AZD1283 919351-41-0 CAS number,AZD1283 Sigma-Aldrich P2Y12 antagonist,AZD1283 bioactive small molecule,AZD1283 chemical for ADP-induced platelet aggregation,AZD1283 for laboratory research,AZD1283 high purity antithrombotic agent,AZD1283 non-nucleotide antagonist,AZD1283 platelet aggregation inhibitor,AZD1283 potent antithrombotic compound,AZD1283 research grade chemical,Ethyl 5-cyano-2-methyl-6-{4-[(benzylsulfonyl)amino]carbonyl}-1-piperidinyl}-3-pyridinecarboxylic acid,Sigma-Aldrich AZD1283 for P2Y12 receptor studies |
| storage temp. | −20°C |
| SMILES string | O=C(OCC)C1=CC(C#N)=C(N2CCC(C(NS(CC3=CC=CC=C3)(=O)=O)=O)CC2)N=C1C |
| InChI | 1S/C23H26N4O5S/c1-3-32-23(29)20-13-19(14-24)21(25-16(20)2)27-11-9-18(10-12-27)22(28)26-33(30,31)15-17-7-5-4-6-8-17/h4-8,13,18H,3,9-12,15H2,1-2H3,(H,26,28) |
| InChI key | NEMHKCNXXRQYRF-UHFFFAOYSA-N |
