产品介绍
Product Description
Application
Aceclofenac (ACE) has been used as an internal standard in the in vivo blood-brain barrier assay. It has also been used to study the interaction of ACE with bovine serum albumin (BSA) by using spectroscopic techniques in combination with computational methods.
Biochem/physiol Actions
Aceclofenac is a phenyl acetic acid derivative used for treating symptoms like swelling, tenderness, and stiffness due to muscle-skeletal and bone-related diseases (rheumatoid arthritis, juvenile arthritis, osteoarthritis, and acute gouty arthritis). This compound shows analgesic and antipyretic properties. Aceclofenac suppresses prostaglandin biosynthesis.
Non-steroidal, anti-inflammatory drug (NSAID), with selectivity for COX-2 over COX-1.
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| color | off-white to light tan |
| solubility | DMSO: ≥20 mg/mL |
| storage temp. | room temp |
| SMILES string | OC(=O)COC(=O)Cc1ccccc1Nc2c(Cl)cccc2Cl |
| InChI | 1S/C16H13Cl2NO4/c17-11-5-3-6-12(18)16(11)19-13-7-2-1-4-10(13)8-15(22)23-9-14(20)21/h1-7,19H,8-9H2,(H,20,21) |
| InChI key | MNIPYSSQXLZQLJ-UHFFFAOYSA-N |
| Gene Information | human ... PTGS2(5743) |
