General description
Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS). The hantavirus nucleocapsid protein plays several roles in viral replication and assembly, and is the major antigen in humoral responses in humans and mice. Within the bunyviridae family, the nucleocapsid protein also functions as an RNA chaperone facilitating the formation of the stable genomic RNA “panhandle” and is thought to aid in the replication of bunyavirus RNA.
Immunogen
Sin Nombre virus nucleocapsid antibody was raised against a 19 amino acid peptide near the center of the Sin Nombre virus nucleocapsid.The immunogen is located within amino acids 170 - 220 of Sin Nombre Virus Nucleocapsid.
Application
Sin Nombre virus nucleocapsid antibody can detect 10ng Sin Nombre virus nucleocapsid peptide in ELISA at 1 μg/ml.
Physical form
Supplied in PBS containing 0.02% sodium azide.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | liquid |
| species reactivity | virus (Sin Nombre virus) |
| concentration | 1 mg/mL |
| technique(s) | ELISA: suitable |
| isotype | IgG |
| UniProt accession no. | Q9E1J8 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | Sin Nombre virus ... SNVsSgp1(2943142) |
