产品介绍
Product Description
General description
The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015]
Immunogen
A phospho specific peptide corresponding to residues surrounding T210 of human PLK1
Physical form
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
技术参数
Specifications
| biological source | rabbit |
| Quality Segment | 100 |
| antibody product type | primary antibodies |
| clone | monoclonal |
| form | liquid |
| species reactivity | mouse, human |
| concentration | 0.98 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt accession no. | P53350 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pThr210) |
| Gene Information | human ... PLK1(5347) |
