产品介绍
Product Description
Biochem/physiol Actions
Celecoxib-NBD is a flourescent COX2-specific inhibitor.
Celecoxib-NBD is a flourescent COX2-specific inhibitor. The molecule binds to, and inhibits COX2 with an IC50 of 0.19 μM, and a selectivity index of 443 for COX2 vs. COX1. Celecoxib-NBD fluorescently labels COX2-expressing HCA-7 colon cells, but not COX2-negative HCT116 cells.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | protect from light |
| color | yellow to orange |
| solubility | DMSO: 10 mg/mL, clear |
| storage temp. | 2-8°C |
