产品介绍
Product Description
General description
UNC10201652 is a potent and substrate-dependent slow-binding inhibitor of bacterial β-glucuronidases (GUSs) in the gut. UNC10201652 appears to target a catalytic intermediate. It alleviates irinotecan-induced gut damage in mouse models of cancer.
Biochem/physiol Actions
potent and selective slow binding inhibitor microbiome β-glucuronidase enzyme
技术参数
Specifications
| form | powder |
| Quality Segment | 100 |
| concentration | ≥98 mg/mL (HPLC) |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | C12=C(N3CCOCC3)N=C(SC4=C5N=NN=C4N6CCNCC6)C5=C1CCCC2 |
| InChI key | ZPVQONCMKZBGTB-UHFFFAOYSA-N |
