产品介绍
Product Description
Biochem/physiol Actions
NRT-870-59 is a potent and selective reversible inhibitor of PTP4A3 tyrosine phosphatase that exhibits potent cytotoxicity against human ovarian and breast cancer cells grown as spheroids. NRT-870-59 does not inhibit oncogenic dual specificity phosphatase CDC25B.
potent and selective reversible inhibitor of PTP4A3 tyrosine phosphatase
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | N=C(C(N1C)=O)C2=C(C=C(C3=CC=CC=C3)S2)C1=O |
| InChI | 1S/C14H10N2O2S/c1-16-13(17)9-7-10(8-5-3-2-4-6-8)19-12(9)11(15)14(16)18/h2-7,15H,1H3 |
| InChI key | IGPZTAJCUQIMOK-UHFFFAOYSA-N |
