产品介绍
Product Description
General description
This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants.
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 784-883 of human KDM5B (NP_006609.3).
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
技术参数
Specifications
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | liquid |
| species reactivity | human, mouse, rat |
| concentration | 2.7 mg/mL |
| technique(s) | immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000 |
| UniProt accession no. | Q9UGL1 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... KDM5B(10765) |
