产品介绍
Product Description
Biochem/physiol Actions
JBSNF-000088 is a cell penetrant, potent and selective inhibitor of Nicotinamide N-methyltransferase (NNMT) that reduces 1-methyl-nicotinamide (MNA) and improved glucose control in mice models of metabolic disease. JBSNF-000088 potently inhibits growth of PFA ependymoma cells.
cell penetrant, potent and selective inhibitor of Nicotinamide N-methyltransferase (NNMT)
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | NC(=O)c1cnc(cc1)OC |
| InChI | 1S/C7H8N2O2/c1-11-6-3-2-5(4-9-6)7(8)10/h2-4H,1H3,(H2,8,10) |
| InChI key | KXDSMFBEVSJYRF-UHFFFAOYSA-N |
