产品介绍
Product Description
General description
Histone demethylase that specifically demethylates ′Lys-9′ of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 ′Lys-4′, H3 ′Lys-27′, H3 ′Lys-36′ nor H4 ′Lys-20′. Only able to demethylate trimethylated H3 ′Lys-9′, with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KDM4B/JMJD2B (O94953).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IF/ICC, IP, ChIP
技术参数
Specifications
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| material | colorless |
| clone | 8I0I1, monoclonal |
| form | liquid |
| mol wt | 150 kDa |
| species reactivity | human, rat |
| concentration | 1.5 mg/mL |
| technique(s) | ChIP: 1:50 - 1:200,immunofluorescence: 1:50 - 1:200,immunoprecipitation (IP): 1:50 - 1:200,western blot: 1:500 - 1:2000 |
| color | colorless |
| isotype | IgG |
| immunogen sequence | PPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWN |
| UniProt accession no. | O94953 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... KDM4B(23030) |
