产品介绍
Product Description
Biochem/physiol Actions
Exo2 acts as a chemical probe of intracellular transport.
Exo2 acts as a chemical probe of intracellular transport. Edxo2 has activities similar to Brefeldin A with membrane trafficking to the Golgi appartus, but appears more selective.
Exo2 is a bioactive small molecule that activates Golgi-endoplasmic reticulum (ER) fusion in mammals by distorting the Golgi apparatus. It prevents the release of secretory cargo from the ER. Exo2 do not modify the morphology of the trans-Golgi network (TGN). It also inhibits the anterograde movement of vesicular stomatitis virus G (VSV G) glycoprotein, from ER to Golgi.
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| color | yellow |
| solubility | DMSO: >20 mg/mL |
| storage temp. | 2-8°C |
| SMILES string | COc1cc(ccc1O)\C=N\Nc2ncnc3sc4CCCCc4c23 |
| InChI | 1S/C18H18N4O2S/c1-24-14-8-11(6-7-13(14)23)9-21-22-17-16-12-4-2-3-5-15(12)25-18(16)20-10-19-17/h6-10,23H,2-5H2,1H3,(H,19,20,22)/b21-9+ |
| InChI key | VFNUTEMVQGLDAG-ZVBGSRNCSA-N |
