General description
PVA polymers are functionalized with thiol-reactive maleimide groups, which react rapidly with thiol groups of crosslinkers to form hydrogels in few seconds. The thiol-reactive maleimide groups are also compatible to conjugate polymers with bioactive factors. The thioglycerol is used to maintain hydrogel strength and also as a control to compare cellular behavior in peptide-modified versus unmodified hydrogels. The buffers (pH7.2 and pH 5.5) are used to control pH and osmotic conditions to optimize time for gelation.
Application
FAST-PVA polymer is used with crosslinkers (CD/PEG crosslinkers) to establish stable hydrogels.
Features and Benefits
- Contains synthetic polymer (PVA) functionalized with maleimide groups for quick gelation
- Non degradable polymer
Other Notes
TRUEPVAF contains FAST-PVA solution in phosphate buffer, TrueGel3D thioglycerol and water.
Disclaimer
Avoid frequent freeze-thaw cycles and store FAST-PVA polymer in small portions.
| biological source | synthetic |
| technique(s) | cell attachment: suitable |
| shipped in | dry ice |
| storage temp. | −70°C |
