产品介绍
Product Description
General description
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at ′Ser-40′ and ′Ser-53′ and then is involved in regulating the initiation of DNA replication during cell cycle.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DBF4 (Q9UBU7).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB
技术参数
Specifications
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| material | colorless |
| clone | 0S8I5, monoclonal |
| form | liquid |
| mol wt | 77 kDa |
| species reactivity | human |
| concentration | 0.35 mg/mL |
| technique(s) | western blot: 1:500 - 1:2000 |
| color | colorless |
| isotype | IgG |
| immunogen sequence | MNSGAMRIHSKGHFQGGIQVKNEKNRPSLKSLKTDNRPEKSKCKPLWGKVFYLDLPSVTISEKLQKDIKDLGGRVEEFLSKDISYLISNKKEAKFAQTLG |
| UniProt accession no. | Q9UBU7 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... DBF4(10926) |
