产品介绍
Product Description
General description
PP2Cγ is a member of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PP2C gamma is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. PP2C gamma is highly expressed in testis, skeletal muscle, and heart. PP2C gamma also plays a main role in regulating cell cycle progression.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Preparation Note
After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
技术参数
Specifications
| recombinant | expressed in baculovirus infected Sf9 cells |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 1920-2880 nmol/min·mg |
| mol wt | ~105 kDa |
| NCBI accession no. | NM_177983 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... PPM1G(5496) |
