General description
Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details. Our extensive collection of normal human primary liver cells includes characterized suspension Hepatocytes, which can be used to model the function of Hepatocytes in vitro. Suspension cells in culture float in media and don’t form a monolayer on the culture surface. We currently offer two options for the characterized suspension Hepatocytes: the mixed gender pool and the single donor. Our pooled suspension Hepatocytes are normalized for cell number to ensure that each donor contributes an equal contribution to the pool. Our single donor human suspension consists of a homogenous population of Hepatocytes.
Application
Primary human suspension hepatocytes are well-suited for in vitro metabolism assays, including enzyme induction studies, as well as investigations into hepatotoxicity, drug screening, transporter efflux activity, and potential drug-drug interactions.
Features and Benefits
Our primary Hepatocytes are isolated from whole human livers, with each donor providing documented consent for research use of non-transplantable organs or tissues. These suspension Hepatocytes cells are cryopreserved for ease of use and undergo testing for enzyme profiling data and ensuring a post-thaw viability of ≥70%. In addition, all cells have been tested for the absence of HIV, HBV, HCV, Syphillis and microbial contaminants (fungi, bacteria, and mycoplasma).
Disclaimer
Each donor is tested and found non-reactive to viral DNA from HIV-1, HIV-2, HTLV I, HTLV II, hepatitis B and hepatitis C. However, no known test can offer complete assurance that the viruses that cause HIV-1, HIV-2, HTLV I, HTLV II, hepatitis B and hepatitis C are not present. Proper precautions and biological containment should be taken when handling cells of human origin, due to their potential biohazardous nature. All human based products should be handled at a BSL-2 (Biosafety Level 2) or higher.
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
| biological source | human liver |
| form | frozen liquid |
| packaging | pkg of 1 vial contains ≥5 million cells |
| technique(s) | cell culture | mammalian: suitable |
| color | cloudy |
| shipped in | liquid nitrogen |
| storage temp. | -140 to -196°C |
