General description
Anti-FGFR2 Antibody detects endogenous levels of total FGFR2 protein.
Fibroblast growth factor receptor 2 (FGFR2), a membrane-spanning tyrosine kinase belongs to the fibroblast growth factor (FGF) family. It is expressed in epithelium, developing central nervous system and in bone rudiments. It is located on human chromosome 10q26.
Immunogen
The antiserum was produced against synthesized peptide derived from human FGFR2.
Immunogen Range: 471-520
Biochem/physiol Actions
Fibroblast growth factor receptor 2 (FGFR2) mutations show poor clinical diagnosis in endometrioid endometrial cancer. The FGFR2 gene participates in directional epithelial-mesenchymal signaling in the endometrium. It is essential for placentation and limb induction.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 92 kDa |
| species reactivity | human, mouse |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:10000,immunohistochemistry: 1:50-1:100,western blot: 1:500-1:1000 |
| NCBI accession no. | P21802 |
| UniProt accession no. | P21802 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... FGFR2(2263) |
