General description
Chemokine receptor CXCR3 also refers as IP -10 or Mig receptor is a Gαi protein-coupled receptor and is highly expressed by IL-2-activated T lymphocytes (Th1). It facilitates calcium mobilization and chemotaxis. It also plays a pivotal role in wound healing. Monoclonal Anti-CXCR3 antibody can be used in flow cytometry for the Identification of CXCR-3. Mouse anti-CXCR3 antibody reacts specifically with CXCR-3 transfected cells but not with the parent cell line. The product has shown no cross-reactivity with human CXCR-1, CXCR-2 and CXCR-4.
Immunogen
human CXCR3 transfected NSO mouse myeloma cells.
Application
Monoclonal Anti-CXCR3 antibody can be used as a positive control in immunohistochemical staining.
Biochem/physiol Actions
The antibody reacts with human CXCR3 transfectant cells and not the parent cell line. It has no cross-reactivity with CXCR1, CXCR2, or CXCR4.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
Preparation Note
Purified using protein G.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 200 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 49801.111, monoclonal |
| form | lyophilized powder |
| species reactivity | human |
| technique(s) | flow cytometry: suitable |
| isotype | IgG1 |
| UniProt accession no. | P49682 |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... CXCR3(2833) mouse ... Cxcr3(12766) |
