产品详情

Erastin2，5MG，SML2794-5MG，Sigma

销售价： ¥ 2665.31 / 件

优惠：请询价

订货号： 0BT2363

品牌型号： SML2794-5MG

货期：询货期

最小订货量： 1件

产品介绍 Product Description

Biochem/physiol Actions

Erastin analog with greatly improved system xc- (SLC7A11/xCT + SLC3A2/4F2hc) inhibitory potency and ferropotosis induction efficacy
Erastin2 is an Erastin analog with greatly improved system xc- (SLC7A11/xCT + SLC3A2/4F2hc) inhibitory potency (Erastin2 IC₅₀ = 3.5 nM/CCF-STTG1; Erastin IC₅₀ = 200 nM/HT-1080, 140 nM/Calu-1; Glu release assay) and ferropotosis induction efficacy (HT-1080 EC₅₀ = 150 nM/Erastin2 vs. 1.2 μM/Erastin).

技术参数 Specifications

Quality Level	100
assay	≥98% (HPLC)
form	powder
color	white to beige
solubility	DMSO: 2 mg/mL, clear
storage temp.	2-8°C
SMILES string	O=C(N(C1=C(OC(C)C)C=CC(C2=CC=CC=C2)=C1)C(CN3CCN(C(COC4=CC=C(Cl)C=C4)=O)CC3)=N5)C6=C5C=CC=C6

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