产品介绍
Product Description
General description
Mupirocin is produced by Pseudomonas fluorescens. Mupirocin is used to treat impetigo and skin infections.
Application
Mupirocin has been used:
- for kinetic assay
- to assess its resistance by performing turbidity assay
- to determine its antimicrobial susceptibility
Biochem/physiol Actions
Antibiotic; inhibits isoleucyl-tRNA synthetase (IRS).
Features and Benefits
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Preparation Note
Mupirocin is poorly soluble in water (26 mg/L), but highly soluble in DMSO (≥10 mg/mL). If sterilization is required, it is advisable to use filter sterilization with a 0.22 µm PTFE, Polypropylene, or Nylon filter membrane.
技术参数
Specifications
| Quality Segment | 100 |
| assay | 920-1020 μg/mg (HPLC) |
| form | crystalline |
| color | white to yellow |
| antibiotic activity spectrum | fungi |
| mode of action | enzyme | inhibits,protein synthesis | interferes |
| originator | GlaxoSmithKline |
| storage temp. | room temp |
| SMILES string | [H][C@@]1(CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC(O)=O)[C@H](O)[C@@H]1O)C[C@@H]2O[C@@]2([H])[C@@H](C)[C@H](C)O |
| InChI | 1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1 |
| InChI key | MINDHVHHQZYEEK-HBBNESRFSA-N |
