General description
Forkhead box protein P1 (FOXP1) is a transcriptional repressor that plays an important role in the development of the brain and lung in mammals. The gene encoding this protein may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene. It is essential transcriptional regulator of B cell development. PAX5/FOXP1 translocation t(9;3)(p13;p14.1) is found in acute lymphoblastic leukemia. FOXP1 is positive in subset of diffuse large B-cell lymphoma and mucosa-associated lymphoid tissue lymphomas.
Immunogen
Synthetic peptide corresponding to the C-terminus of human FOXP1 protein.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| recombinant | expressed in proprietary host |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | SP133, monoclonal |
| species reactivity | human (tested) |
| species reactivity (predicted by homology) | rat, frog, mouse, bovine, chicken |
| technique(s) | flow cytometry: 1:100,immunoblotting: 1:25,immunohistochemistry: 1:100 |
| isotype | IgG |
| UniProt accession no. | Q9H334 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | human ... FOXP1(27086) |
