General description
The mouse monoclonal antibody 1A5 recognizes CD170 (Siglec-5, sialic acid binding Ig-like lectin 5), a transmembrane glycoprotein expressed strongly by neutrophils, macrophages activated during infections, monocytes, and dendritic cells. As in case with other anti-CD170 antibodies, this antibody crossreacts with Siglec-14, whose first two Ig domains are almost identical to those of CD170.
Immunogen
Fusion protein composed of human CD170 extracellular domain and Fc region of human IgG1
Physical form
Solution in phosphate buffered saline with 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 1A5, monoclonal |
| form | buffered aqueous solution |
| species reactivity | nonhuman primates, human |
| concentration | 1 mg/mL |
| technique(s) | flow cytometry: 2 μg/mL |
| accession no. | NP_003821.1 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | human ... SIGLEC5(8778) |
