General description
Anti-TNFRSF10B / TRAILR2 / CD262 Reference Antibody, expressed from CHO cells, featuring a heavy chain type of huIgG1 and a light chain type of hulambda, has a predicted MW of 145.5 kDa. This antibody is valuable across various research applications. It facilitates ELISA assays for quantifying TNFRSF10B / TRAILR2 / CD262 expression levels, FACS for precise cell sorting, kinetic studies to analyze its binding properties, functional assays to assess its biological activity, and utilization in animal models to evaluate its efficacy and safety profiles in vivo. These applications offer comprehensive insights into its potential therapeutic applications, particularly in cancer research and immunotherapy.
Immunogen
DR5
Packaging
100ug/vial; 1mg/vial
Preparation Note
For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake it to solubilize the protein completely. Do not vortex.
Upon receipt, store immediately at -20°C for 24 months in lypholized state. -80°C for 12 months after reconstitution. Avoid repeated freeze-thaw cycles.
| recombinant | expressed in CHO cells |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody product type | primary antibodies |
| clone | recombinant monoclonal |
| form | lyophilized |
| species reactivity | macaque (Cynomolgus), human |
| concentration | 1 mg/mL |
| technique(s) | ELISA: 0.0001 -10 μg/mL |
| optimum pH | 6.2 |
| pH range | 5.5 -6.14 |
| immunogen sequence | MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIEDHLLSSGKFMYLEGNADSAMS |
| Protein ID accession no. | NP_003833 |
| UniProt accession no. | O14763 |
| storage temp. | -65 to -96°C |
| target post-translational modification | unmodified, unmodified |
| Gene Information | human ... TNFRSF10B(8795) |
