产品介绍
Product Description
Biochem/physiol Actions
BRL 50481 is a potent and selective PDE7 inhibitor (IC50 = 260 nM).
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Legal Information
Sold for research purposes under agreement from GlaxoSmithKline
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| color | white to off-white |
| solubility | DMSO: >10 mg/mL,H2O: insoluble |
| originator | GlaxoSmithKline |
| storage temp. | 2-8°C |
| SMILES string | CN(C)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O |
| InChI | 1S/C9H12N2O4S/c1-7-4-5-8(11(12)13)6-9(7)16(14,15)10(2)3/h4-6H,1-3H3 |
| InChI key | IFIUFCJFLGCQPH-UHFFFAOYSA-N |
| Gene Information | human ... PDE7A(5150), PDE7B(27115) |
