General description
Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS). Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins G1 (Gn) and G2 (Gc). The G1 glycoprotein is is thought to be degraded by the host autophagy machinery, and this autophagic clearance is required for efficient virus repliaction.
Immunogen
Sin Nombre virus glycoprotein 1 antibody was raised against a 19 amino acid peptide near the amino terminus of the Sin Nombre virus glycoprotein.The immunogen is located within amino acids 60 - 110 of Sin Nombre Virus Glycoprotein 1.
Application
Sin Nombre virus glycoprotein 1 antibody can detect 10ng Sin Nombre virus glycoprotein 1 peptide in ELISA at 1 μg/ml.
Physical form
Supplied in PBS containing 0.02% sodium azide.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | liquid |
| species reactivity | virus (Sin Nombre virus) |
| concentration | 1 mg/mL |
| technique(s) | ELISA: suitable |
| isotype | IgG |
| NCBI accession no. | NP_941974 |
| UniProt accession no. | Q89905 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | Sin Nombre virus ... SNVsMgp1(2654026) |
