产品介绍
Product Description
General description
Lidocaine hydrochloride monohydrate is a commonly used as local anesthetic in topical applications and oral mucosal biopsies. It has a short anesthetic half-life.
Application
Lidocaine hydrochloride monohydrate has been used:
- in the preparation of drug composite for the controlled delivery in vitro, evaluated by drug release profile in ultra-high performance liquid chromatography (UPLC) and as a reference standard for fourier transform infrared spectroscopy (FT-IR).
- to record dose dependent response of sodium voltage (Nav1.7) channels in the injection-molded polymer device.
- For inhibition of glial cells in brain tissue samples.
Biochem/physiol Actions
Na+ 通道阻滞剂；IB 类抗心律失常药，在肠胃外给药后迅速吸收
Na+ 通道阻滞剂；IB 类抗心律失常药。
技术参数
Specifications
| form | solid |
| Quality Level | 200 |
| color | white |
| solubility | H2O: soluble |
| SMILES string | Cl[H].[H]O[H].CCN(CC)CC(=O)Nc1c(C)cccc1C |
| InChI | 1S/C14H22N2O.ClH.H2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H;1H2 |
| InChI key | YECIFGHRMFEPJK-UHFFFAOYSA-N |
| Gene Information | human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335) |
