General description
This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 343-442 of human GATA4 (NP_002043.2).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Application
Immunofluorescence Analysis: A 1:100 dilution from a representative lot detected GATA-4 inhuman small intestine and proliferative duodenum intestinal organoid tissue sections.
WB, IHC
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| material | colorless |
| clone | 1M2E4, monoclonal |
| form | liquid |
| mol wt | 55 kDa |
| species reactivity | human, rat |
| concentration | 0.5 mg/mL |
| technique(s) | immunofluorescence: suitable,immunohistochemistry: 1:100 - 1:500,western blot: 1:500 - 1:1000 |
| color | colorless |
| isotype | IgG |
| immunogen sequence | ASGASSNSSNATTSSSEEMRPIKTEPGLSSHYGHSSSVSQTFSVSAMSGHGPSIHPVLSALKLSPQGYASPVSQSPQTSSKQDSWNSLVLADSHGDIITA |
| UniProt accession no. | P43694 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... GATA4(2626) |
